Table 3.
Comparison of patient characteristics between the two groups before treatment
| Variables | Matched group (n = 198) |
SGLT2-inhibitor group (n = 135) |
t/χ2 | P -alue |
|---|---|---|---|---|
| Smoking history | 67 (33.84%) | 56 (41.48%) | 2.01 | 0.156 |
| Drinking history | 59 (29.80%) | 33 (24.44%) | 1.15 | 0.283 |
| Diabetic family history | 10 (5.05%) | 9 (6.67%) | 0.39 | 0.532 |
| Age (years) | 60.11 ± 11.73 | 59.14 ± 9.47 | -0.83 | 0.406 |
| Male | 142 (71.72%) | 102 (75.56%) | 0.60 | 0.437 |
| MBI (kg•m− 2) | 26.28 ± 2.42 | 26.62 ± 2.09 | 1.36 | 0.174 |
| HbA1c (%) | 5.15 ± 0.60 | 5.25 ± 0.57 | 1.63 | 0.105 |
| FPG (mmol/L) | 4.92 ± 0.99 | 5.04 ± 0.81 | 1.30 | 0.195 |
| 2hGP/(mmol/L) | 7.12 ± 0.44 | 7.09 ± 0.65 | -0.43 | 0.669 |
| eGFR (ml/min) | 102.84 ± 9.40 | 104.87 ± 13.75 | 1.49 | 0.138 |
| UA (µmmol/L) | 344.50 ± 52.12 | 346.67 ± 70.63 | 0.30 | 0.761 |
| ALT (U/L) | 34.16 ± 24.12 | 30.66 ± 15.94 | -1.60 | 0.112 |
| TC (mmol/L) | 5.05 ± 1.83 | 5.34 ± 1.39 | 1.63 | 0.105 |
| TG (mmol/L) | 2.12 ± 1.03 | 1.97 ± 0.65 | -1.62 | 0.106 |
| LDL-C (mmol/L) | 2.58 ± 1.26 | 2.77 ± 1.20 | 1.40 | 0.163 |
| LVEF (%) | 36.91 ± 1.93 | 36.91 ± 1.90 | 1.30 | 0.195 |
Data are represented as n (%) or x ± s. BMI, body mass index; HbA1c, hemoglobin A1c; FPG, fasting plasma glucose; 2hPG, 2 h postprandial blood glucose; eGFR, estimated glomerular filtration rate; UA, uric acid; ALT, alanine aminotransferase; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction