Table 2.
Liver transplant evaluation data, %
|
|
Delayed
|
Early
|
P value
|
| Transferred to center | 48.7 | 51.2 | 0.75 |
| MELD-Na (points) | 27.2 (7) | 27.0 (9) | 0.87 |
| TIPS placed | 15.4 | 7.3 | 0.22 |
| ICU stay | 51.3 | 43.9 | 0.35 |
| ICU d (#) | 10 (9) | 8 (7) | 0.44 |
| Pressor support | 34.6 | 26.8 | 0.29 |
| Declined for LT listing | 17.9 | 15.9 | 0.72 |
| Reasons declined | |||
| Psychosocial | 30.0 | 12.5 | 0.38 |
| Medical | 20.0 | 25.0 | |
| Death | 30.0 | 12.5 | |
| Other | 20.0 | 50.0 | |
| Decompensations | |||
| Ascites | 94.9 | 96.3 | 0.65 |
| Jaundice | 64.1 | 72.0 | 0.29 |
| EVB | 21.8 | 24.4 | 0.70 |
| HE | 70.7 | 70.5 | 0.98 |
| HRS | 59.8 | 62.8 | 0.69 |
| HHT | 21.8 | 14.6 | 0.24 |
| SBP | 21.8 | 18.3 | 0.58 |
| ACLF grade | |||
| Grade 1 | 34.6 | 42.7 | 0.56 |
| Grade 2 | 50.0 | 42.7 | |
| Grade 3 | 15.4 | 14.6 | |
| ACLF bilirubin | |||
| < 15 mg/dL | 82.1 | 76.8 | 0.28 |
| 15-25 mg/dL | 9.0 | 17.1 | |
| > 25 mg/dL | 9.0 | 6.1 | |
| ACLF INR | |||
| < 1.8 | 62.8 | 62.2 | 0.78 |
| 1.8-2.5 | 28.2 | 25.6 | |
| > 2.5 | 9 | 12.2 | |
| ACLF lactate | |||
| < 1.5 mmol/L | 73.1 | 80.5 | 0.16 |
| 1.5-2.5 mmol/L | 15.4 | 6.1 | |
| > 2.5 mmol/L | 11.5 | 13.4 | |
| ACLF creatinine | |||
| < 0.7 mg/dL | 7.3 | 7.3 | 0.64 |
| 0.7-1.5 mg/dL | 32.9 | 32.9 | |
| > 1.5 mg/dL | 52.6 | 59.8 |
Clinical data from index admission and liver transplant evaluation. Data reported as percentages of group for categorical data; as average (standard deviation) for normally distributed continuous data. Comparisons were made using students T tests and comparison of proportions test. ACLF: Acute on chronic liver failure; LT: Liver transplant; ICU: Intensive care unit; MELD: Model for end stage liver disease; TIPS: Trans-jugular intrahepatic portosystemic shunt; EVB: Esophagogastric variceal bleeding; HRS: Hepatorenal syndrome; HHT: Hepatic hydrothorax; SBP: Spontaneous bacterial peritonitis; LTE: Liver transplant evaluation; INR: International normalized ratio; HE: Hepatic encephalopathy.