Table 1.
Demographic criteria of the study participants (n = 90)
|
Variable
|
Control (n = 30), mean ± SD
|
P value
|
Late-PE (n = 30), mean ± SD
|
Early-PE (n = 30), mean ± SD
|
P value
|
| Age (yr) | 26.53 ± 1.18 | 0.39 NS | 28.33 ± 1.34 | 28.67 ± 0.99 | 0.39 NS |
| BMI (kg/m2) | 24.93 ± 0.34 | 0.77 NS | 26.19 ± 0.29 | 26.96 ± 3.42 | 0.77 NS |
| Gestational age (wk) | 34.93 ± 0.20b | 0.0001 | 36.30 ± 0.19a | 30.70 ± 0.34c | 0.0001 |
| Systolic BP (mmHg) | 106.00 ± 1.48b | 0.0001 | 152.33 ± 1.71a | 152.33 ± 1.64a | 0.0001 |
| Diastolic BP (mmHg) | 82.67 ± 1.85b | 0.0001 | 103.00 ± 1.80a | 102.66 ± 1.79a | 0.0001 |
| Mean arterial BP (MAP) | 90.44 ± 1.21b | 0.0001 | 119.44 ±1.69a | 119.22 ± 1.65a | 0.0001 |
| AST (IU/L) | 23.09 ± 1.07b | 0.05 | 34.05 ± 5.98a | 27.25 ± 1.41ab | 0.05 |
| ALT (IU/L) | 17.82 ± 0.88b | 0.0001 | 30.06 ± 2.75a | 25.17 ± 1.45a | 0.0001 |
| Urea (mg/dL) | 25.01 ± 1.32 | 0.84 NS | 25.93 ± 1.56 | 26.21 ± 1.64 | 0.84 NS |
| Creatinine (mg/dl) | 0.665 ± 0.02b | 0.0001 | 0.759 ± 0.02a | 0.759 ± 0.02a | 0.0001 |
| Albumin in urine | - | 0.19 NS | 460.50 ± 47.06 | 381.66 ± 35.43 | 0.19 NS |
| Hemoglobin (g/dL) | 12.68 ± 0.19a | 0.0001 | 11.69 ± 0.19b | 12.02 ± 0.21b | 0.0001 |
| Platelets counts × 109 L | 287.60 ± 11.23a | 0.0006 | 182.83 ± 10.48b | 204.90 ± 10.70b | 0.0006 |
| Elabela (pg/mL) | 18.36 ± 0.43a | 0.002 | 11.05 ± 0.22b | 7.61 ± 0.19c | 0.002 |
The highest difference.
Moderate difference.
Least difference.
The analysis was conducted using ANOVA, where the P value represents the difference among the three groups. To show which group has the highest difference, we use letters a, b, and c. If the three groups have no difference between them, then the letter used is the same. BMI: Body mass index; BP: Blood pressure; AST: Aspartate aminotransferase; ALT: Alanine transaminase; NS: Not significant.