Table 1.
Prediction models for rebleeding in small bowel bleeding
Ref.
|
Prediction model
|
Variables
|
Rebleeding rate
|
Niikura et al[38], 2016 | Prediction model using 5 factors | Female sex, liver cirrhosis, use of warfarin, overt bleeding, hemoglobin below 10 g/dL, positive CE findings | 0% with 0 variable; 8.7% with 1 variable; 14.7% with 2 variables; 30.4% with 3 variables; 40.0% with 4 variables |
Originally created by O’Brien et al[39], 2015; tested by Cúrdia Gonçalves et al[40], 2018 | ORBIT score | Age ≥ 75 yr, hemoglobin (< 12 g/dL for women, < 13 g/dL for men), prior GI bleeding or intracranial hemorrhage, reduced kidney function (GFR < 60 mg/dL/1.73 m2), use of antiplatelets | 45% in low/intermediate risk group; 80% in high risk group; AUROC is 0.67 when cutoff value of 4 |
Uchida et al[37], 2018 | PRSBB score | Age, sex, type of bleeding (occult or overt), transfusion requirement, cardiovascular disease, liver cirrhosis, CE findings, type of treatment | 3.63% in low risk group; 12.8% in intermediate risk group; 23.4% in high risk group |
Ohmiya et al[41], 2019 | Ohmiya index | Angina pectoris, arrhythmia, congestive heart failure, chronic kidney disease, peripheral vascular disease, hemodialysis, valvular heart disease, hereditary vascular disease, portal hypertensive disease | 33% in small bowel vascular disease predicted by score ≥ 2 |
de Sousa Magalhães et al[45], 2020 | RHEMITT score | Renal disease (GFR mL/min), heart failure, endoscopic findings, major bleeding, incomplete CE, tobacco consumption, treatment by endoscopy | 0.00% in low risk group; 25.4% in intermediate risk group; 63.8% in high risk group |
AUROC: Area under the receiver operating characteristics curve; CE: Capsule endoscopy; GI: Gastrointestinal; GFR: Glomerular filtration rate; ORBIT: Outcomes Registry for Better Informed Treatment; PRSBB: Predicting Rebleeding in Small Bowel Bleeding; RHEMITT: Renal disease, Heart failure, Endoscopic findings, Major bleeding, Incomplete CE, Tobacco consumption, Treatment by endoscopy.