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. 2023 Jun 28;21:164. doi: 10.1186/s12964-023-01134-z

Table 8.

Intratumoural microbiota that can be targeted

Intratumoural microbiota Characteristics Results References
C.butyricum Capable of spontaneous aggregation within Colorectal cancer tissue Promising anti-tumor efficacy coupled with relatively low toxicity and adverse effects [119]
Clostridium Colonization and proliferation are limited to anoxic TME Promising anti-tumor efficacy [120]
Salmonella, Escherichia In the TME with relatively high oxygen content, colonization and proliferation were observed Promising anti-tumor efficacy [120]
Listeria Monocytogenes Combined with radionuclide 188 rhenium (188Re) to provide radioactivity to pancreatic cancer metastasis Good anti-tumor effect without serious side effects [122]