Table 9.

Intratumoural microbiota that can cooperate with immunotherapy

Intratumoural microbiota	Mechanism	Cancer	References
Bifidobacterium	Local delivery of bifidobacteria effectively stimulates STING signaling and increases crossover initiation of dendritic cells following anti-CD47 treatment, thereby influencing treatment	Colorectal cancer	[20]
Enterococcus faecalis	Promoting TH1 differentiation of CD4 + T cells and CD8 + T-cell activation	Pancreatic Cancer	[22]
E. coli Top10	Induction of tumor-specific CD4 + and CD8 + T cells	Colorectal cancer	[124]