Table 2.
Patient characteristics.
| Characteristic | RM-ON, N = 133a | RM-OFF, N = 108a | p-valueb |
|---|---|---|---|
| Age | 54 (28, 71) | 64 (48, 76) | 0.007 |
| Male | 91 (68%) | 65 (60%) | 0.2 |
| Smoke | 33 (26%) | 21 (23%) | 0.6 |
| Familiarity of sudden death | 17 (13%) | 12 (13%) | 0.9 |
| History of arrhythmia | 19 (15%) | 18 (19%) | 0.4 |
| Hypertension | 58 (45%) | 38 (41%) | 0.5 |
| Dyslipidemia | 35 (27%) | 20 (22%) | 0.3 |
| Coronary artery disease | 16 (12%) | 11 (12%) | 0.9 |
| Chronic obstructive pulmonary disease | 12 (9.3%) | 17 (18%) | 0.05 |
| Diabetes | 10 (7.8%) | 12 (13%) | 0.2 |
| Previous stroke or TIA | 5 (3.9%) | 5 (5.4%) | 0.7 |
| Atrial fibrillation | 14 (11%) | 14 (15%) | 0.4 |
| Chronic kidney disease | 8 (6.2%) | 8 (8.6%) | 0.5 |
| Palpitations | 29 (22%) | 22 (24%) | 0.8 |
| History of syncope | 133 (100%) | 108 (100%) | |
| Total number of syncope | 2 (1, 4) | 3 (2, 4) | 0.06 |
| Prodromes | 57 (43%) | 30 (33%) | 0.14 |
| Presyncope | 39 (29%) | 24 (26%) | 0.6 |
| Trauma | 36 (27%) | 23 (26%) | 0.8 |
| Resting heart rate | 70 (62, 80) | 70 (65, 75) | 0.6 |
| Systolic blood pressure | 120 (111, 130) | 120 (115, 128) | 0.9 |
| Left ventricle ejection fraction (%) | 59 (55, 60) | 55 (55, 60) | 0.5 |
| Medical therapy | |||
| ACE inhibitors | 32 (25%) | 22 (22%) | 0.6 |
| Angiotensin receptor blockers | 14 (11%) | 10 (9.9%) | 0.8 |
| Beta blockers | 35 (28%) | 30 (30%) | 0.7 |
| Diuretics | 15 (12%) | 10 (9.9%) | 0.6 |
| Calcium antagonists | 16 (13%) | 8 (7.9%) | 0.3 |
| Antiplatelets | 22 (17%) | 20 (20%) | 0.6 |
| Anticoagulants | 12 (9.4%) | 2 (2.0%) | 0.020 |
| Antiarrhythmic class IC agents | 6 (4.7%) | 5 (5.0%) | 0.9 |
| Amiodarone | 3 (2.4%) | 1 (1.0%) | 0.6 |
| Sotalol | 5 (3.9%) | 2 (2.0%) | 0.5 |
| Insulin | 19 (15%) | 16 (16%) | 0.9 |
ACE, angiotensin-converting enzyme; TIA, transient ischemic attack.
a
Median (interquartile range) or n (%).
b
Wilcoxon rank sum test, Pearson's Chi-squared test, or Fisher's exact test.