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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Mechanisms of activation of an antigen presenting cell through a DNA vaccine. This activation can be either directly (endogenous via) or through an intermediate cell that captures the plasmid and produces the pathogen antigen that will be recognized by the APC (exogenous via).