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. 2023 Jun 13;15(6):1719. doi: 10.3390/pharmaceutics15061719

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Illustration of ²²⁵Ac-PSMA-617 treatment in chemotherapy-naive patients with advanced prostate cancer. A patient presenting with advanced prostate cancer exhibited a complete response post 3 treatment cycles with ²²⁵Ac-PSMA-617. The patient remained symptom-free at an 11-month follow-up, with his serum PSA remaining below the detectable level and the follow-up ⁶⁸Ga-PSMA-11 PET/CT scan remaining negative for disease recurrence [43].