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. 2023 Jun 13;11(6):1097. doi: 10.3390/vaccines11061097

Table 5.

Association of the risk factors with different type of common adverse effects after receiving vaccines.

Factors Type of Adverse Effects
Fever Headache Fatigue/
Muscle Pain
Pain at Site
Odds Ratio p-Value Odds Ratio p-Value Odds Ratio p-Value Odds Ratio p-Value
Age group Both doses 0.598 0.598 0.925 0.402
18–34 years old 1 1 1 1
35–54 years old 0.81
(0.44–1.56)
0.81
(0.44–1.56)
0.9
(0.49–1.73)
1.03
(0.68–1.56)
55–73 years old 0.67
(0.27–1.59)
0.67
(0.27–1.59)
0.87
(0.38–1.98)
1.34
(0.79–2.27)
Dose 1 0.598 0.598 0.925 0.402
18–34 years old 1 1 1 1
35–54 years old 0.81
(0.44–1.56)
0.81
(0.44–1.56)
0.9
(0.49–1.73)
1.03
(0.68–1.56)
55–73 years old 0.67
(0.27–1.59)
0.67
(0.27–1.59)
0.87
(0.38–1.98)
1.34
(0.79–2.27)
Dose 2 0.598 0.598 0.925 0.402
18–34 years old 1 1 1 1
35–54 years old 0.81
(0.44–1.56)
0.81
(0.44–1.56)
0.9
(0.49–1.73)
1.03
(0.68–1.56)
55–73 years old 0.67
(0.27–1.59)
0.67
(0.27–1.59)
0.87
(0.38–1.98)
1.34
(0.79–2.27)
Gender Both doses 0.192 0.192 0.462 0.693
Male 1 1 1 1
Female 1.37
(0.85–2.18)
1.37
(0.85–2.18)
1.18
(0.75–1.86)
0.94
Dose 1 0.192 0.192 0.462 0.693
Male 1 1 1 1
Female 1.37
(0.85–2.18)
1.37
(0.85–2.18)
1.18
(0.75–1.86)
0.94
Dose 2 0.192 0.192 0.462 0.693
Male 1 1 1 1
Female 1.37
(0.85–2.18)
1.37
(0.85–2.18)
1.18
(0.75–1.86)
0.94
Dose 1 by vaccine Astra 1 0.032 * 1 0.032 * 1 0.097 1 <0.0001 *
Moderna 1.79
(0.94–3.37)
1.79
(0.94–3.37)
1.47
(0.78–2.7)
1.75
(1.17–2.64)
Pfizer 1.95
(1.08–3.52)
1.95
(1.08–3.52
1.74
(0.99–3.02)
2.17
(1.48–3.18)
Dose 2 by vaccine Astra 1 0.423 1 0.423 1 0.676 1 0.005 *
Moderna 1.5
(0.77–2.92)
1.5
(0.77–2.92)
1.27 1.69
(1.1–2.6)
Pfizer 1.25
(0.7–2.27)
1.25
(0.7–2.27)
1.21 1.71
(1.19–2.45)
Two doses by vaccines Two doses are not the same 1 0.035 * 1 0.035 * 1 0.115 1 <0.0001 *
Two doses are Astra 2.04
(0.74–7.03)
2.04
(0.74–7.03)
1.68
(0.69–4.72)
1.03
(0.62–1.73)
Two doses are Moderna 3.15
(1.1–11.07)
3.15
(1.1–11.07)
2.2
(0.86–6.4)
1.82
(1.05–3.2)
Two doses are Pfizer 3.41
(1.24–11.69)
3.41
(1.24–11.69)
2.59
(1.06–7.26)
2.22
(1.31–3.82)
Consistency of two doses Two doses are different vaccines 1 0.034 * 1 0.034 * 1 0.08 1 0.125
Two doses are the same vaccines 2.64
(1.04–6.71)
2.64
(1.04–6.71)
2.02
(0.91–4.51)
1.4
(0.91–2.17)

(*) p < 0.05.