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The relative propensity to induce prostanoid-associated periorbitopathy (PAP) symptoms or other ocular and adjacent tissue cosmetic alterations by four different FP-receptor agonists and an EP2-receptor agonist, OMDI, following topical ocular treatment in ocular hypertensive or glaucoma patients is displayed. The overall severity of the changes induced is shown on a relative scale or graded format ranging from Grade 0 to Grade 3.
