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AUC0–24 ratio of CBD and THC in rat whole-blood and brain after a single oral dose of Cannabis sativa extract at 30 mg/kg (cannabidiol equivalent dose) in the solvents Cremophor EL [Kolliphor® EL, pH-range 6.0–8.0, Sigma Aldrich]/ethanol/saline solution (1:1:18) formulation and Rapae oleum.
| CBD | Rapae oleum | AUCbrain:AUC whole blood | 1.54 |
| Cremophor | AUCbrain:AUC whole blood | 0.95 | |
| THC | Rapae oleum | AUCbrain:AUC whole blood | 3.72 |
| Cremophor | AUCbrain:AUC whole blood | 1.22 |
