. 2023 Jun 14;10:1216733. doi: 10.3389/fmolb.2023.1216733

TABLE 2.

Nano-systems for enhancing the antitumor activity of ionizing radiation.

Nano-system	Type of metal	Cell lines	In vivo evaluation	References
HPNPs	Iron	Mouse melanoma B16F10 cells	Mouse melanoma B16F10 tumors	Lin et al. (2023)
HPNPs	Iron	Mouse normal L929 fibroblasts	Mouse melanoma B16F10 tumors	Lin et al. (2023)
FPH	Iron	Mouse mammary carcinoma 4T1 cells	Mouse mammary 4T1 tumors	Hou et al. (2023)
FPH	Iron	Mouse RAW264.7 macrophages	Mouse mammary 4T1 tumors	Hou et al. (2023)
Fe₂O₃@TA-Pt	Iron	Mouse mammary carcinoma 4T1 cells	Mouse mammary 4T1 tumors	Jiang et al. (2022)
Fe₂O₃@TA-Pt	Iron	Normal human HUVEC cells	Mouse mammary 4T1 tumors	Jiang et al. (2022)
GOD@FeN₄-SAzyme	Iron	Mouse mammary carcinoma 4T1 cells	Mouse mammary 4T1 tumors	Zhu et al. (2022)
SPIONC	Iron	Human lung cancer NCI-H460 cells	Human lung cancer NCI-H460 tumors	Li et al. (2022)
iCoDMSN	Cobalt	Mouse mammary carcinoma 4T1 cells	Mouse mammary 4T1 tumors	Zhao et al. (2023)
		Human breast cancer MCF-7 cells
		Human lung cancer A549 cells
		Human colorectal cancer Caco-2 cells
		Human gastric carcinoma SGC-7901 cells
AGulX	Gadolinium	Human breast cancer MDA-MB-231 cells	Human breast cancer MDA-MB-231 tumors	Sun et al. (2022)
AGulX	Gadolinium	Human breast cancer MDA-MB-468 cells	Human breast cancer MDA-MB-231 tumors	Sun et al. (2022)
3a	Gold	Human cervical carcinoma HeLa cells	Human cervical carcinoma HeLa cells transplanted in zebrafish	Yang et al. (2022)
3a	Gold	Human cervical carcinoma SiHa cells		Yang et al. (2022)
PBmB-DOX	Bismuth	Mouse mammary carcinoma 4T1 cells	Mouse mammary 4T1 tumors	Hou et al. (2022)