TABLE 3.
Gene signatures associated to ionizing radiation.
| Gene signature | Tumor types | Cell line validation | Pathway involved | References |
|---|---|---|---|---|
| MAPK1 | Malignant glioblastoma | U87 | IL-17 | Xie et al. (2022) |
| ZEB1 | U251 | Cytokine-cytokine receptor interaction | ||
| MAP1LC3A | TNF signaling pathways | |||
| HSPB1 | DCs | |||
| CA9 | Macrophages | |||
| STAT3 | TIL | |||
| TNFAIP3 | Treg cells | |||
| SCL7A11 | Breast cancer | MCF7 | SLC7A11/ESR1 | Liu et al. (2022) |
| ZR-75-1 | SLC7A11/NEDD4L | |||
| MDA-MB-231 | ||||
| ACSL3 | Prostate cancer | No | Epithelial–mesenchymal transition | Feng et al. (2022) |
| EPAS1 | Allograft rejection | |||
| FASN | Fc gamma R-mediated phagocytosis | |||
| GSTP1 | TGF beta signaling | |||
| LDHB | ECM receptor interaction | |||
| NEDD4L | Adipocytokine signaling | |||
| Androgen response | ||||
| Notch signalling |