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. 2023 Jun 6;16(6):848. doi: 10.3390/ph16060848

Figure 1.

Figure 1

Impact of meloxicam on the depression manifestations evoked by chronic restraint stress (CRS) in animals. Herein, the depression manifestations were improved by meloxicam in the sucrose preference test (SPT) and forced swimming test (FST). The higher sucrose intake percentage in the SPT (A) and diminished immobility time (B) in the FST were indicators of meloxicam’s beneficial outcomes. Calculation of the Z-values is detailed in Section 4.5.5 (Materials and Methods). Bars express mean ± standard deviation (n = 6). **** p < 0.0001 or * p < 0.05 vs. control; #### p < 0.0001 vs. CRS (one-way ANOVA and Tukey’s multiple comparison test). CRS, chronic restraint stress; MLX, meloxicam.