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. Author manuscript; available in PMC: 2023 Jun 28.
Published in final edited form as: Occup Environ Med. 2019 Jul 13;76(11):827–837. doi: 10.1136/oemed-2018-105655

Table 2:

Cohort specific and Meta HR for the Association between Animal Farming and the Risk of Overall LHC

AGRICAN CNAP AHS Meta
  No HRa 95% CI No. HRb 95% CI No. HRc 95% CI No. Meta HR 95% CI I2
Any animal 564 1.15 0.95,1.41 1443 0.98 0.89,1.09 409 1.05 0.90,1.22 2416 1.03 0.95,1.11 5.3
Cattle 526 0.99 0.78,1.25 1008 1.00 0.91,1.09 270 1.04 0.89,1.21 1804 1.01 0.93,1.08 0.0
No. of cattle
<30 172 0.91 0.72,1.15 792 0.98 0.89,1.08 - - - 964 0.97 0.89,1.06 0.0
30+ 354 1.02 0.74,1.41 216 1.06 0.91,1.23 - - - 570 1.05 0.92,1.21 0.0
P - trend 0.99 0.71 - - - 0.73
Dairy cattle 425 1.04 0.87,1.25 864 0.99 0.90,1.08 31 1.01 0.70,1.45 1320 1.00 0.92,1.08 0.0
Beef cattle 740 1.00 0.91,1.10 247 1.02 0.87,1.19 987 1.00 0.93,1.09 0.0
Sheep/goat 134 0.75 0.56,1.01 1968 0.96 0.88,1.05 24 1.20 0.80,1.81 805 0.93 0.77,1.13 47.4
No. of sheep/ goat
<35 78 0.82 0.70,0.97 438 0.94 0.85,1.05 78 - - 438 0.89 0.78,1.02 46.7
35+ 57 1.00 0.62,1.61 343 0.98 0.87,1.10 57 - - 343 0.98 0.87,1.10 0.0
P - trend 0.05 0.54 - - - 0.30
Pigs 289 0.84 0.71,1.00 580 0.95 0.86,1.04 194 1.14 0.96,1.35 1063 0.97 0.83,1.12 67.9
No of Pigs
<35 205 0.88 0.74,1.04 440 0.90 0.81,1.00 205 - - 645 0.89 0.83,1.12 0.0
35+ 83 0.64 0.36,1.11 140 1.14 0.96,1.36 83 - - 233 0.91 0.52,1.59 73.6
P - trend 0.05 0.91 - - - 0.39
Poultry 344 0.89 0.73,1.08 552 1.12 1.01,1.23 60 1.04 0.80,1.36 956 1.03 0.88,1.19 53.3
No of poultry
<100 223 0.77 0.63,0.95 412 1.08 0.96,1.20 30 1.29 0.89,1.87 665 1.00 0.77,1.30 78.8
100+ 121 1.16 0.85,1.58 140 1.25 1.05,1.49 17 0.74 0.46,1.20 278 1.11 0.86,1.42 51.0
P, trend 0.76 0.01 0.61 0.10
Livestock 552 1.10 0.91,1.33 1414 0.99 0.89,1.09 395 1.04 0.89,1.21 2361 1.02 0.94,1.10 0.0
No. of livestock
<100 344 0.83 0.52,1.31 - - 122 0.88 0.71,1.10 466 0.87 0.71,1.06 0.0
100+ 204 0.95 0.73,1.24 - - 248 1.15 0.95,1.39 452 1.07 0.89,1.29 24.9
P, trend 0.87 , 0.14 0.14

Abbreviations: CI, confidence interval; HR, hazard ratio; No., number of exposed cases, - , not collected by this cohort

a

HR: AGRICAN - Cox Regression adjusted for: sex, retirement status, the number of crops for which farmer/worker personally applied pesticides

b

HR: CNAP - Myeloid neoplasms - Cox Regression adjusted for: sex, Aldicarb, Lindane, DDT, Mancozeb

b

HR: CNAP - Lymphoid neoplasms - Cox Regression adjusted for: sex, Dichlorvos, Aldicarb, Lindane, DDT, Deltametrin, Mancozeb, Linuron, Glyphosate

c

HR: AHS - Myeloid neoplasms - Cox Regression adjusted for: sex, state, Chlorpyrifos, Terbufos, Dichlorvos, Dicamba, Glyphosate, Lindane, DDT, Aldicarb, Captan

c

HR: AHS - Lymphoid neoplasms - Cox Regression adjusted for: sex, state, Terbufos, Lindane, DDT, Permethrin, Dicamba, Parathion, Carbaryl