Table 4.

Characteristics of the included studies.

No	Author, Year	Study Design	Participants	Inclusion Criteria	Exclusion Criteria	Intervention	Duration of Intervention
1	Narkwichean et al., 2017 [14]	Randomized Controlled Trial	Total: 52 (27 DHEA, 25 placebo)	-Aged > 23 years -Predicted Diminished Ovarian Reserve (DOR) by AFC < 10 and/or serum AMH < 5 pmol/L -Regular menstrual cycle	-Obesity with BMI > 35 kg/m2 -History of oophorectomy -With untreated hydrosalpinx, endometrial polyp or submucous myoma at beginning of treatment -With endocrinological disorders for, e.g., thyroid/adrenal disease -Allergy to DHEA -Treated with insulin for diabetic management	DHEA 75 mg/day	Minimum 12 weeks
2	Tsui et al., 2014 [13]	Prospective Cohort	Total: 10	PORs, met Bologna Criteria [12]	-History of ovarian cystectomy -History of oophorectomy -History of cytotoxic treatment or pelvic irradiation for malignancy -Taking herbal drugs or other hormonal agents	DHEA(exact dose not mentioned)	NA
3	Lin et al., 2017 [15]	Prospective Cohort	Total: 6	PORs, met Bologna Criteria [12] and had failed IVF cycle	-History of oophorectomy -History of cytotoxic treatment or pelvic irradiation for malignancy -Taking herbal drugs or other hormonal agents	DHEA 90 mg/day	Minimum 2 months
4	Lin et al., 2017 [18]	Prospective Case-Control	Total: 88≤37 yrs: 30≥37 yrs: 58 (28 with DHEA, 30 without)	Infertile women underwent IVF within study period	-History of oophorectomy -History of exposure to cytotoxic or pelvic irradiation for malignancy -Taking herbal drugs or other hormonal agents	DHEA 90 mg/day	Minimum 2 months
5	Lin et al., 2017 [16]	Prospective Case-Control	Total:131NORs: 59PORs: 72 (34 with DHEA, 38 No DHEA)	-Normal Ovarian Response (NORs) -PORs, met Bologna Criteria [12]	Not mentioned	DHEA 90 mg/day	8–16 weeks
6	Li et al., 2021 [19]	Prospective Case-Control	Total: 77≤ 38 yrs: 32>38 yrs: 45(20 with DHEA, 25 without)	-Infertile patient underwent IVF within study period	-History of oophorectomy -Donor cycle -Had pelvic radiotherapy or chemotherapy -Taken hormonal therapy within the last 3 months	DHEA 25 mg/3 times daily	Minimum 8 weeks
7	Hou et al., 2022 [17]	Prospective Case-Control	Total:60NORs: 22PORs: 38 (18 with DHEA, 20 No DHEA)	-NORs -PORs, met Bologna Criteria [12]	-History of oophorectomy -Donor cycle -Had pelvic radiotherapy or chemotherapy -Taken hormonal therapy within the last 3 months	DHEA 25 mg/3 times daily	Minimum 2 months