Table 6.

Clinical outcome of the included studies.

Study Author	Narkwichean et al. [14]	Tsui et al. [13]	Lin et al. [15]	Lin et al. [18]	Lin et al. [16]	Li et al. [19]	Hou et al. [17]
Comparison	DHEA vs. Non-DHEA	Post-DHEA	Post vs. Pre-DHEA	Older group DHEA vs. No DHEA	PORs group DHEA vs. No DHEA	Older group DHEA vs. No DHEA	PORs group DHEA vs. No DHEA
Stimulation Outcomes
Stimulation Duration (Days)	12.5 (10–17) vs. 13 (10–14); p = 0.81	NA	10.3 ± 2.2 vs. 9.8 ± 2.5; p = 0.64	10.9 ± 1.9 vs. 10.3 ± 2.2	NA	NA	10.5 ± 1.5 vs. 12.1 ± 2.2
Gonadotrophin doses (IU)	3801.6 ± 1007.9 vs. 3802.2 ± 678.9; p = 0.99	NA	3150.0 ± 264.02 vs. 2950.0 ± 745.0; p = 0.49	3139.3 ± 595.7 vs. 2910.0 ± 813.3	NA	NA	2795.4 ± 684.1 vs. 2775.1 ± 806.9
Cycle Outcomes
N. of oocytes retrieved	med (IQR): 4, 0–18 vs. 4, 0–15; p = 0.54	p < 0.01	3.17 ± 1.60 vs. 2.00 ± 1.10; p = 0.17	3.5 ± 2.1 vs. 2.4 ± 1.3	3.5 ± 2 vs. 2.3 ± 1.2	5.2 ± 1.4 vs. 3.2 ± 2.1; p < 0.05	3.8 ± 2.1 vs. 3.2 ± 2.2; p < 0.05
N. of MII oocytes retrieved	NA	NA	1.67 ± 0.82 vs. 0.50 ± 0.55; p < 0.05	2.3 ± 1.7 vs. 1.2 ± 1.0	2.2 ± 1.6 vs. 1.1 ± 0.9	2.3 ± 1.5 vs. 1.8 ± 1.7	2.7 ± 1.2 vs. 1.4 ± 2.5
Fertilization rate (%)	64.5 ± 24.9 vs. 48.0 ± 30.4; p = 0.052	NA	75.6 ± 28.5 vs. 22.2 ± 27.2; p < 0.01	76.8 vs. 55.4; p < 0.05	75.9 vs. 58.8; p < 0.05	71.7 ± 22.0 vs. 67.8 ± 21.2	76.5 ± 21.2 vs. 66.2 ± 11.2
N. of day 3 embryos	NA	p < 0.0001	2.17 ± 0.98 vs. 0.67 ± 0.82; p < 0.05	NA	NA	3.4 ± 1.6 vs. 1.7 ± 2.1; p < 0.05	3.5 ± 1.5 vs. 1.5 ± 2.2; p < 0.05
N. of top-quality D3 embryos	NA	NA	NA	1.2 ± 1.1 vs. 0.3 ± 0.6	1.2 ± 1.1 vs. 0.3 ± 0.6; p < 0.05	2.4 ± 1.7 vs. 0.7 ± 1.2; p < 0.05	1.9 ± 1.7 vs. 0.7 ± 1.5; p < 0.05
Pregnancy Outcomes
Clinical pregnancy rate (%)	8 ± 30 vs. 9 ± 36; p = 0.63	NA	NA	17.7 vs. 4.8	18.7 vs. 5.2	26.3 vs. 16	27.7 vs. 15.0
Ongoing pregnancy rate (%)	NA	NA	NA	NA	15.6 vs. 2.6	26.3 vs. 16	22.2 vs. 15.0
Live birth rate (%)	7 ± 26 vs. 8 ± 32; p = 0.63	NA	NA	NA	12.9 vs. 2.6	16.7 vs. 12	22.2 vs. 10.0

NA: not availaible.