TABLE 1.
Major families of AMPs primarily targeting the S. aureus membrane
Structural class | No. of peptides (n = 115) | Eminent examples of AMP families |
---|---|---|
α-helical | 48 | Dermaseptin-B2, aurein 2.5, magainin 2, melittin, buforin II, LL-37, chrysophsin-1 |
β-sheets | 10 | Lactoferricin B, baboon theta-defensin-1, human neutrophil peptide-1, gomesin, protegrin 1, tachyplesin I, and kalata B1 |
α + β | 6 | Human beta-defensin 1, thrombocidin-1, porcine beta-defensin 2, CXCL10, actinomycesin |
Non-αβ | 3 | Pyrrhocoricin, penisin, and tridecaptin A1 |