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. 2023 May 23;13(6):540. doi: 10.3390/membranes13060540

Table 2.

Top three clusters with their representative enriched identifier or terms [one per cluster]. Count is the number of DEPs with membership in the given reactome gene set identifier or gene ontology [GO] term. % is the percentage of all DEPs that are found in the given ontology term [only input proteins with at least one ontology term annotation are included in the calculation]. Log10[P] is the p-value in log base 10. Log10[q] is the multi-test adjusted p-value in log base 10. PATTERN shows the color code used for the protein lists where the term is found to be statistically significant, i.e., the multiple colors indicate a pathway/process that is shared across the three DEP lists [Red-SKBR-3; Blue-BT474; Green-MDA-MB-361]. The analysis was performed by tools available at https://metascape.org, accessed on 27 October 2022.

PATTERN Identifier/Term Category Descrlptlon Count % Log10(P) Log10(q)
R-HSA-556833 Reactome Gene Sets metabolism of lipids 36 8.98 −10.5 −6.15
GO:0090407 GO Biological Processes organophosphate biosynthetic process 28 6.98 −8.89 −4.84
GO:0043414 GO Biological Processes macromolecule methylation 11 7.97 −7.18 −3.13