Table 7.
Urinary cypermethrin metabolites (GM(GSD), nmole/g creatinine) of conventional farmers, classified by age, sex, insecticide use at home in the past 1 year, cypermethrin use on their farm, and the use of insecticides at home (Aswin, Ars, Baygon, Shieldtox, and the mosquito coil) did not report taking a bath immediately after spraying, kept all used chemical containers at home for disposal, and had a daily intake of vegetables.
3-PBA | Cis-DCCA | Trans-DCCA | Cis,trans-DCCA | Total Cypermethrin | ||||||
---|---|---|---|---|---|---|---|---|---|---|
GM (GSD) | p-Value | GM (GSD) | p-Value | GM (GSD) | p-Value | GM (GSD) | p-Value | GM (GSD) | p-Value | |
Age 1 | ||||||||||
1. <35 | 4.14 (3.30) | 0.287 | 12.07 (2.50) | 0.090 | 6.82 (2.52) | 0.016, (1–2) p = 0.013, (1–3) p = 0.046 |
20.16 (2.26) | 0.053, (1–2) p = 0.042 |
24.94 (2.33) | 0.056, |
2. 35–60 | 6.33 (3.25) | 18.76 (2.41) | 11.84 (2.41) | 31.74 (2.31) | 39.45 (2.33) | (1–2) p = 0.044 | ||||
3. >60 | 6.09 (3.58) | 18.22 (2.57) | 11.88 (2.13) | 30.96 (2.29) | 38.15 (2.38) | |||||
Sex 2 | ||||||||||
Male | 5.67 (3.41) | 0.241 | 16.35 (2.50) | 0.022 * | 10.87 (2.47) | 0.477 | 28.46 (2.36) | 0.112 | 35.32 (2.40) | 0.119 |
Female | 7.08 (3.02) | 22.61 (2.25) | 12.00 (2.22) | 35.18 (2.19) | 43.63 (2.20) | |||||
Insecticide use at home in the past 1 year 2 | ||||||||||
Yes | 5.89 (3.33) | 0.480 | 18.11 (2.26) | 0.389 | 11.21 (2.37) | 0.791 | 30.43 (2.29) | 0.544 | 37.46 (2.33) | 0.831 |
No | 7.13 (3.26) | 15.21 (2.84) | 10.63 (2.73) | 27.11 (2.66) | 35.94 (2.64) | |||||
Cypermethrin use on the farm 2 | ||||||||||
Yes | 9.77 (2.66) | <0.001 * | 24.37 (2.28) | <0.001 * | 12.76 (2.39) | 0.040 * | 37.82 (2.25) | <0.001 * | 48.52 (2.33) | <0.001 * |
No | 3.97 (3.38) | 13.60 (2.41) | 9.94 (2.38) | 24.74 (2.27) | 29.83 (2.30) | |||||
Type of insecticide used at home | ||||||||||
ARS 2,3 | ||||||||||
Yes | 9.24 (2.54) | 0.052 | 25.31 (2.18) | 0.043 * | 12.46 (2.27) | 0.515 | 38.02 (2.18) | 0.151 | 48.04 (2.17) | 0.123 |
No | 5.58 (3.45) | 17.22 (2.44) | 11.02 (2.41) | 29.41 (2.31) | 36.20 (2.36) | |||||
Baygon 2,3 | ||||||||||
Yes | 8.03 (2.93) | <0.001 * | 21.02 (2.46) | 0.008 * | 12.54 (2.36) | 0.043 * | 34.74 (2.29) | 0.012 * | 43.83 (2.31) | 0.004 * |
No | 4.05 (3.57) | 14.92 (2.30) | 9.67 (2.40) | 25.59 (2.25) | 30.75 (2.30) | |||||
Shieldtox 2,3 | ||||||||||
Yes | 5.89 (3.61) | 0.958 | 17.12 (2.46) | 0.734 | 11.63 (2.49) | 0.816 | 29.98 (2.34) | 0.924 | 36.94 (2.42) | 0.914 |
No | 5.98 (3.33) | 18.27 (2.43) | 11.14 (2.38) | 30.49 (2.30) | 37.68 (2.34) | |||||
Mosquito coil 2,3 | ||||||||||
Yes | 6.09 (3.29) | 0.662 | 18.69 (2.43) | 0.358 | 11.61 (2.37) | 0.289 | 31.57 (2.29) | 0.245 | 38.86 (2.32) | 0.307 |
No | 5.54 (3.64) | 16.18 (2.41) | 9.89 (2.46) | 26.61 (2.33) | 33.31 (2.43) | |||||
Did not take a bath immediately after spraying 2 | ||||||||||
Yes | 11.12 (2.20) | <0.001 * | 25.32 (2.25) | <0.001 * | 13.69 (2.32) | 0.014 * | 40.07 (2.18) | <0.001 * | 52.01 (2.15) | <0.001 * |
No | 4.34 (3.49) | 14.77 (2.44) | 10.01 (2.41) | 25.85 (2.31) | 31.32 (2.35) | |||||
Kept all used chemical containers at home for disposal 2 | ||||||||||
Yes | 9.25 (2.48) | <0.001 * | 22.44 (2.27) | <0.001 * | 12.34 (2.30) | 0.092 | 35.41 (2.22) | 0.005 * | 45.42 (2.22) | <0.001 * |
No | 3.88 (3.66) | 14.06 (2.52) | 10.06 (2.49) | 25.49 (2.36) | 30.57 (2.40) | |||||
Daily vegetable intake 2 | ||||||||||
Yes | 7.25 (3.04) | 0.007 * | 20.28 (2.47) | 0.013 * | 12.40 (2.39) | 0.039 * | 34.16 (2.30) | 0.010 * | 42.65 (2.32) | 0.008 * |
No | 4.63 (3.56) | 14.84 (2.39) | 9.63 (2.38) | 25.22 (2.28) | 31.02 (2.33) |
1 Multiple comparisons with the Tukey scores on the natural logs of metabolite concentration; p-value refers to the overall ANOVA and p-value of each subgroup; 2 t-test on the natural logs of metabolite concentration. 3 Main ingredients of insecticide used at home. ARS sprays contain imiprothrin 0.2%, cypermethrin 0.1% [21]. Baygon sprays contain cypermethrin (0.1%) and other pyrethroids, imiprotin (0.03%), and prallethrin (0.03%) [22]. Shieldtox sprays contain other pyrethroids, prallethrin 0.076%, and D-phenothrin 0.046% [23]. Mosquito coils have different brands with different active ingredients, but the main active ingredients are also pyrethroids, dimefluthrin, allethrin, metofluthrin, etc. [24,25]. * Significant at a p-value < 0.05.