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. 2023 Apr 25;66(1):e40. doi: 10.1192/j.eurpsy.2023.24

Table 2.

Moderation effects on study outcomes.

Outcome Moderator k N Estimate (95% CI) SE Inline graphic Inline graphic P
Psychopathology Baseline ( Inline graphic : 0.52, 0.06) 14 56 0.28 (0.14, 0.42) 0.07
Clinical setting 14 56 0.26 1.00 0.004*
 Inpatients 4 15 –0.05 (−0.28, 0.19) 0.12
 Outpatients 10 41 0.43 (0.29, 0.57) 0.07
Comparison group 14 56 0.22 1.00 0.008*
 Occupational therapy 2 8 0.49 (0.16, 0.81) 0.17
 Treatment as usual 11 45 0.29 (0.16, 0.42) 0.07
Video games 1 3 −0.61 (−1.19, −0.03) 0.30
Quality of life Baseline ( Inline graphic : 0.11, 0.59) 9 28 0.30 (−0.05, 0.65) 0.18
Clinical setting 9 28 0.17 0.88 0.004*
 Inpatients 3 7 0.89 (0.52, 1.26) 0.19
 Outpatients 6 21 −0.07 (−0.36, 0.23) 0.15
Intervention group 9 28 0.31 1.00 0.012*
 Aerobic exercise 3 6 0.80 (0.45, 1.14) 0.18
 High-intensity interval training 1 3 0.77 (0.27, 1.28) 0.26
 Light–moderate aerobic exercise 3 16 −0.24 (−0.41, −0.07) 0.09
 Yoga 2 3 0.23 (−0.18, 0.64) 0.21
Comparison group 9 28 0.11 0.44 0.14
Follow-up 9 28 0.90 0.08 0.008*
 No 7 26 0.22 (−0.12, 0.55) 0.17
 Yes 2 2 1.11 (0.46, 1.77) 0.33
Anthropometric measurements and composition Baseline ( Inline graphic : 0.00, 0.06) 9 20 0.10 (−0.10, 0.30) 0.10
Clinical setting 9 20 0.00 0.84 0.24
Intervention group 9 20 0.00 1.00 0.32
Comparison group 9 20 0.00 1.00 0.55
Cardiorespiratory fitness Baseline ( Inline graphic : 0.00, 0.47) 10 28 0.13 (−0.24, 0.51) 0.16
Clinical setting 10 28 0.00 0.80 0.01*
Inpatients 3 6 0.21 (−0.16, 0.50) 0.14
Outpatients 7 22 0.31 (0.02, 0.61) 0.15
Intervention group 10 28 0.00 1.00 0.051
Comparison group 10 28 0.00 0.00 0.19
ADL Baseline ( Inline graphic : 0.00, 0.04) 7 13 0.26 (0.09, 0.43) 0.09
Clinical setting 7 13 0.00 1.00 0.14
Intervention group 7 13 0.00 1.00 0.42
Comparison group 7 13 0.00 0.00 0.72
Cognitive function Baseline ( Inline graphic : 0.21, 0.71) 6 47 0.01 (−0.55, 0.58) 0.29
Intervention group 6 47 0.00 0.18 0.88
Comparison group 6 47 0.00 0.15 0.49
Follow-up 6 47 0.10 0.00 0.11
Muscular strength Baseline ( Inline graphic : 0.00, 0.00) 3 6 0.52 (0.22, 0.81) 0.15
Clinical setting 3 6 0.00 0.00 0.43
Intervention group 3 6 0.00 0.00 0.64
Comparison group 3 6 0.00 0.00 0.35
Physical function Baseline ( Inline graphic : 0.91, 0.00) 8 17 0.50 (−0.07, 1.06) 0.29
Clinical setting 8 17 0.00 0.00 0.96
Intervention group 8 17 0.06 0.00 0.88
Comparison group 8 17 0.06 0.00 0.49
Follow-up 8 17 0.06 0.00 0.11
Physical health biomarkers Baseline ( Inline graphic : 0.37, 0.17) 7 25 0.05 (−0.24, 0.33) 0.14
Clinical setting 7 25 0.10 0.07 0.51
Intervention group 7 25 0.29 1.00 0.13
Comparison group 7 25 0.75 0.00 0.036*
Occupational therapy 3 10 0.34 (−0.07, 0.75) 0.21
Treatment as usual 3 13 −0.24 (−0.66, 0.18) 0.22
Video games 2 2 −0.09 (−0.97, 0.79) 0.45
Follow-up 7 25 0.00 0.54 0.52
Psychological biomarkers Baseline ( Inline graphic : 0.26, 0.00) 3 4 −0.12 (−0.40, 0.17) 0.15
Clinical setting 3 4 0.36 0.00 0.30
Intervention group 3 4 1.00 0.00 0.20
Stress and anxiety Baseline ( Inline graphic : 0.00, 0.00) 2 3 0.14 (−0.11, 0.40) 0.13
Intervention group 2 3 0.00 0.00 0.98

Note: Clinical setting moderated whether patients were inpatients or not. Intervention group moderated for the type of exercise prescribed. Comparison group moderated for what was giving to the control condition. Follow-up moderated for whether a post-intervention evaluation was carried out or not. If not all the moderators appeared in a variable, it could mean that (a) the studies that provided the data for them did not have that moderator in common; (b) all the included studies of the same outcome included the same class of a specific moderator; or (c) were removed from the meta-analysis model because of the great amount of uncertainty that introduced.

k, number of studies; N, number of effects from those studies; SE, standard error.

*

P-value < 0.05.