Skip to main content
. 2023 Jun 20;13(6):772. doi: 10.3390/metabo13060772
HE hepatic encephalopathy
TNF tumor necrosis factor
IL interleukin
ALF acute liver failure
MHE minimal hepatic encephalopathy
NSAIDS non-steroidal anti-inflammatory drugs
CCL C-C motif chemokine ligand
CXCL C-X-C motif chemokine ligand
NO nitric oxide
CNS central nervous system
BBB blood–brain barrier
TJs tight-junctions
C1q complement 1q
GFAP glial fibrillary acid protein
NF-kB nuclear factor kappa B
SCFAs short chain fatty acids
FXR farnesoid X receptor
NK natural killer
SIBO small intestinal bacterial overgrowth
GABA gamma-aminobutyric acid
MELD model for end-stage liver disease
MRI magnetic resonance imaging
LPS lipopolysaccharides
PAMPs pathogen-associated molecular patterns
TLR toll-like receptor
MyD88 myeloid differentiation primary response 88
GF germ free
FMT fecal microbiota transplantation
CD cluster of differentiation
mRNA messengerRNA
AOM azoxymethane
TGF transforming growth factor
TGFβR2 transforming growth factor β-receptor2
COX cyclooxygenase
iNOS inducible nitric oxide synthase
cGMP glutamate-(NO)-cyclic guanosine monophosphate
BDL bile duct ligation
PET positron emission tomography
PBBS peripheral benzodiazepine binding sites
CD cluster of differentiation
NAFLD non-alcoholic fatty liver disease
NMDA N-methyl-D-aspartate
AMPA α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
CUMS chronic unpredictable mild stress
NH4+ ammonium
Nrf2/HO-1 nuclear factor erythroid 2-relatted factor-2/heme oxygenase-1
SNr substantia nigra pars reticulata
PCS portacaval shunts
GLT glutamate transporters
MAPK p30 mitogen-activated protein kinase
CTP Child Turcotte Pugh
BCAAs branched chain amino acids