Table 2.
SDH subunit fragility based on SIFT.
| SDH subunit (L)a | Aligned positionsb (P) | Positions tolerating four or fewer substitutions (S) | Fraction (P/S) | 
|---|---|---|---|
| A (622) | 475 | 246 | 0.52 | 
| B (252) | 187 | 106 | 0.57 | 
| C (140) | 100 | 38 | 0.38 | 
| D (103) | 93 | 49 | 0.53 | 
Bold indicates greatest value in column.
aMature subunit length in amino acids; bNumber of amino acid positions with SIFT alignment score of 1.0.
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