Table 1.
Baseline characteristics and results. Data are presented as mean ± s.d.
Lean subjects (n = 18) | Obese subjects (n = 18) | P-value | |
---|---|---|---|
Age (years) | 24.1 ± 5.3 | 28.4 ± 5.8 | 0.03 |
Height (cm) | 180.3 ± 6.5 | 178.9 ± 7.0 | 0.52 |
Weight (kg) | 72.8 ± 7.6 | 113.8 ± 14.5 | <0.001 |
BMI (kg/m2) | 22.3 ± 1.3 | 35.6 ± 4.7 | <0.001 |
Waist circumference (cm) | 87.9 ± 5.7 | 120.6 ± 13.8 | <0.001 |
Systolic blood pressure (mm Hg) | 133.9 ± 11.3 | 138.4 ± 13.2 | 0.29 |
Diastolic blood pressure (mm Hg) | 76.7 ± 8.8 | 83.7 ± 11.6 | 0.06 |
Fat mass (kg) | 10.7 ± 4.0 | 36.6 ±11.1 | <0.001 |
Lean mass (kg) | 62.1 ± 6.6 | 77.1 ± 6.8 | <0.001 |
Resting energy expenditure (kcal/24 h) | 1936 ± 328 | 2325 ± 465 | 0.007 |
Diet-induced energy expenditure (kcal/24 h) | 779 ± 405 | 896 ± 385 | 0.40 |
Cortisol baseline (nmol/L) | 340 ± 107 | 349 ± 170 | 0.85 |
Cortisol peak (nmol/L) | 475 ± 124 | 419 ± 125 | 0.18 |
Maximum cortisol increase (nmol/L) | 134.7 ± 99.7 | 69.6 ± 135.5 | 0.10 |
Cortisol 3 h AUC | 60,334 ± 18001 | 55,409 ± 16994 | 0.40 |
AUC, area under the curve; BMI, body mass index.