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. 2022 Oct 29;7:100097. doi: 10.1016/j.lansea.2022.100097

Table 3.

Number of infections averted via pre-exposure prophylaxis (PrEP) use (2015–2032) in comparison to no PrEP.

Cumulative starters Consistent use (%)
10% 20% 30% 40% 50%
120,000 995 (1.9%) 1355 (2.5%) 1680 (3.1%) 2075 (3.9%) 2405 (4.5%)
100,000 810 (1.5%) 1120 (2.1%) 1365 (2.5%) 1675 (3.1%) 1955 (3.6%)
80,000 675 (1.3%) 895 (1.7%) 1100 (2.0%) 1330 (2.5%) 1540 (2.9%)
60,000 525 (1.0%) 695 (1.3%) 840 (1.6%) 1025 (1.9%) 1160 (2.2%)
40,000 370 (0.7%) 455 (0.8%) 530 (1.0%) 635 (1.2%) 710 (1.3%)

The analysis are stratified by percentage of users using PrEP consistently from 2021 onwards. We defined consistent use as daily PrEP use with 95% effectiveness of PrEP, with high retention (average duration of five years) in the PrEP programs. Non-consistent PrEP use has an effectiveness of 85%.