Table 1.
Characteristics of study population at each step of the study.
| Steps of evaluation | Variables | All subjects (1st step evaluation) (n = 79,957) |
Subjects at risk of Metabolic disorder (2nd step evaluation) (n = 9819) |
Subjects with Metabolic disorder (3rd step evaluation) (n = 1403) |
|---|---|---|---|---|
| 1st Step | Age (year); median (IQR) | 41 (29, 51) | 45 (34, 55) | 44 (34, 54) |
| Men; n (%) | 37,055 (46.3) | 3690 (37.6) | 763 (54.4) | |
| Literate subjects; n (%) | 8883 (11.1) | 235 (2.4) | 230 (16.4) | |
| BMI (kg/m2); median (IQR) | 19.4 (17.5, 21.8) | 20.3 (18, 23) | 21.23 (5.3) | |
| Subjects with BMI <23 kg/m2; n (%) | 66,525 (83.2) | 7342 (74.8) | 920 (65.6) | |
| Waist circumference (cm); median (IQR) | 71 (65, 78) | 75 (68, 82) | 78 (70, 86) | |
| Subjects with abdominal obesity; n (%) | 11,279 (14.1) | 2336 (23.8) | 394 (28.1) | |
| Hypertensive; n (%) | 33,016 (41.3) | 6060 (61.7) | 929 (66.2) | |
| RBG (mg/dL) >200 mg/dL; n (%) | 1332 (1.7) | 460 (4.7) | 175 (12.5) | |
| 2nd Step | FBG (mg/dL); Median (IQR) | NA | 87 (79, 99) | 107 (87, 132) |
| Subjects with elevated FBG; n (%) | NA | |||
| (a) All subjects with FBG ≥100 mg/dL | 2431 (24.8) | 939 (66.9) | ||
| (b) IFG/Prediabetes | 1656 (16.9) | 461 (32.9) | ||
| (c) Diabetes | 775 (7.9) | 478 (34.0) | ||
| ALT (IU/L); Median (IQR) | NA | 20 (14, 29) | 35 (20, 52) | |
| Subjects with elevated ALT; n (%) | NA | 3881 (39.5) | 958 (68.3) | |
| 3rd Step | TG (mg/dl); Median (IQR) | NA | NA | 142 (122, 167) |
| MU subjects; n (%) | NA | NA | 885 (63.1) | |
| Subjects with MS; n (%) | NA | NA | 268 (19.1) | |
| MU Subjects with persistently elevated ALT; n (%) | NA | NA | 470/885 (53.0) |
ALT, Alanine Aminotransferase; DM, Diabetes Mellitus; FBG, Fasting Blood Glucose; IFG, Impaired fasting Glucose (Prediabetes); IQR, interquartile range expressed as 25th and 75th percentile values, respectively; MS, Metabolic Syndrome (defined by the guideline of International Diabetes Federation (IDF)); MU Metabolically Unhealthy; NA, Not Applicable; RBG, Random Blood Glucose; TG, Triglyceride.
Abdominal obesity was defined as waist circumference ≥90 cm in male and ≥80 cm in female, specific for South-Asian ethnicity; MU subjects were defined as having metabolic risk factors ≥2.