Table 2.
Tumorigenicity of established PDOX models during serial subransplantation between male and female SCID mice.
Tumor type | Model number | Total mouse number | Passages |
---|---|---|---|
GBM | 18 (34a) | 467 | II-VII |
MB | 18 (33) | 523 | II-V |
ATRT | 5 (10) | 120 | II-V |
EPN | 6 (8) | 91 | II-V |
DIPG | 7 (20) | 310 | II-VII |
PNET | 5 (7) | 84 | II-V |
Total | 59 (112) | 1595 | II-VII |
Model number including different passages in vivo.