Fig 3. Expression of six Zinc lncRNAs in Ae. aegypti mosquitoes after a Zika virus-infected vs. non-infected blood meal.

Data were collected at three different time points (2, 7, and 14 days post-blood-feeding). Comparisons were made between Zika virus-infected and non-infected samples at the same time point. On average, in infected samples, 7dpi Zinc1 was upregulated 6.6-fold, Zinc2 was up-regulated 15.4-fold, Zinc3 8.6-fold, Zinc9 17.1-fold, and Zinc10 10.9-fold, whereas Zinc22 was down-regulated 7.0-fold at 2dpi. Each sample contained three biological replicates. Expression values are transcript-level read counts, normalized for library size using the median-by-ratio method. Bars indicate mean value ± SEM. The significance was determined by Student’s t-test. *:P<0.05, **:P<0.01, ***:P<0.001