Table 3.
Distribution of F5 p.Arg534Gln genotypes by adjudicated ACEI-AE and ARB-AE status
Group | Arg534 only (n) | 534Gln carriers (n) | Total (n) | Association |
---|---|---|---|---|
ACEI-AE/ARB-AE | 326 | 61 | 387 | Odds ratio = 2.85 |
ACEI/ARB controls | 609 | 37a | 646 | 95% CI, 1.89–4.25 |
Total | 935 | 98 | 1,033 | P value 1.53 × 10−7 |
ACEI, angiotensin-converting enzyme inhibitor; AE, adverse event; ARB, angiotensin receptor blocker.
One homozygous for 534Gln.