Table 1.

Average absolute and relative organ weights and splenic cellularity in female and male C57BL/6 mice given PFOA by gavage for 15 days

	Females		Males
	0 mg/kg	7.5 mg/kg	0 mg/kg	7.5 mg/kg
Body weight (g)	19.65 ± 0.86	20.78 ± 0.58	25.45 ± 0.60	20.78 ± 0.58
Absolute organ weight
Liver (mg)	910.0 ± 0.02	2260 ± 0.09*	1280 ± 0.04	3140 ± 0.13*
Spleen (mg)	116.3 ± 12.11	81.0 ± 4.43*	90.0 ± 0.00	65.0 ± 0.00*
Relative (organ weight/body weight) organ weight
Liver	46.9 ± 2.37	108.4 ± 2.14*	50.2 ± 1.32	152.1 ± 7.14*
Spleen	6.2 ± 1.06	3.8 ± 0.13	3.6 ± 0.12	2.9 ± 0.23
Splenic cellularity
Cell counts	7.55 ± 6.18 × 107	5.50 ± 4.83 × 107*	6.04 ± 3.87 × 107	4.80 ± 2.73 × 107*

^*A statistical (p < .05) difference from match-sex control group.

N = 8 animals/group.