Table 2.
Weight parameters and other phenotypes in male ACI, BN, BUF, F344, M520, and WKY rats (mean ± SEM (N))
| Phenotype | ACI |
BN |
BUF |
F344 |
M520 |
WKY |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vehicle | BPF | Vehicle | BPF | Vehicle | BPF | Vehicle | BPF | Vehicle | BPF | Vehicle | BPF | |
| Tissue measurements | ||||||||||||
| Adrenal glands (mg) | 38.6 ± 0.8 (12) | 39.2 ± 0.6 (13) | 50.4 ± 1.2 (10) | 50.5 ± 1.0 (10) | 37.4 ± 0.4 (10) | 37.2 ± 0.4 (11) | 45.6 ± 1.2 (12) | 45.1 ± 0.9 (12) | 38.7 ± 1.0 (12) | 37.7 ± 0.9 (12) | 48.4 ± 1.1 (13) | 51.6 ± 0.9 (14) |
| Adrenal glands (µg/g) | 178 ± 4 (12) | 181 ± 2 (13) | 205 ± 4 (10) | 205 ± 4 (11) | 110 ± 1 (10) | 109 ± 1 (11) | 159 ± 4 (12) | 157 ± 3 (12) | 163 ± 3 (12) | 159 ± 1 (12) | 160 ± 3 (13) | 173 ± 2 (14)* |
| Testes (g) | 2.2984 ± 0.0158 (12) | 2.3068 ± 0.0252 (13) | 2.9931 ± 0.0382 (9) | 3.0345 ± 0.0340 (10) | 3.0345 ± 0.0253 (10) | 3.0388 ± 0.0239 (11) | 3.0032 ± 0.0217 (12) | 2.9680 ± 0.0260 (12) | 2.5570 ± 0.0407 (12) | 2.5192 ± 0.0304 (12) | 2.5957 ± 0.0153 (15) | 2.5836 ± 0.0215 (15) |
| Testes (mg/g) | 10.599 ± 0.066 (12) | 10.659 ± 0.154 (13) | 12.171 ± 0.212 (9) | 12.557 ± 0.171 (10) | 8.944 ± 0.114 (10) | 8.905 ± 0.065 (11) | 10.432 ± 0.109 (12) | 10.333 ± 0.061 (12) | 10.757 ± 0.161 (12) | 10.652 ± 0.115 (12) | 8.645 ± 0.092 (15) | 8.682 ± 0.066 (15) |
| Thyroid gland (mg) | 9.5 ± 0.4 (12) | 11.0 ± 0.2 (12) | 9.8 ± 0.6 (9) | 9.4 ± 0.5 (11) | 14.0 ± 0.6 (10) | 14.8 ± 0.3 (11) | 11.6 ± 0.3 (12) | 11.8 ± 0.4 (12) | 16.2 ± 0.6 (12) | 16.2 ± 0.7 (12) | 11.3 ± 0.4 (12) | 11.7 ± 0.5 (12) |
| Thyroid gland (µg/g) | 43.9 ± 1.7 (12) | 50.3 ± 0.9 (13)* | 40.1 ± 1.9 (9) | 38.2 ± 1.9 (11) | 41.4 ± 1.9 (10) | 43.3 ± 1.1 (11) | 40.4 ± 1.0 (12) | 41.0 ± 1.2 (12) | 68.1 ± 2.1 (12) | 68.1 ± 2.2 (12) | 37.5 ± 1.2 (12) | 39.3 ± 1.8 (12) |
| Circulating hormones | ||||||||||||
| Plasma total testosteronea (ng/ml, Log10) | 1.9 ± 0.1 (6) | 1.9 ± 0.1 (7) | 1.2 ± 0.0 (9) | 1.4 ± 0.1 (11) | 2.3 ± 0.2 (6) | 2.1 ± 0.1 (8) | 1.5 ± 0.2 (7) | 1.5 ± 0.1 (7) | 1.7 ± 0.2 (5) | 1.7 ± 0.2 (4) | 2.1 ± 0.2 (7) | 2.0 ± 0.1 (7) |
Relative tissue weights are per gram body weight.
a
Total testosterone data were transformed by log10 to meet normality requirement for statistical comparison. Comparisons made between vehicle and BPF animals of the same strain done by two-way ANOVA with Šídák’s multiple comparisons test. Significant differences highlighted in bold.
*
p < .05.