(d).

Authors	Year	Country	Region	Study design	Setting	Sample size	Number of cases	Burden/10000	Duration of study/months	Quality of study
Theron et al. [61]	2020	South Africa	Southern Africa	Cross-sectional	Hospital-based	223,388	77	3.44	60	Medium
Ugwu et al. [36]	2007	Nigeria	Western Africa	Cross-sectional	Hospital-based	2891	31	127.98	37	Medium
Venter et al. [62]	1995	South Africa	Southern Africa	Cross-sectional	Hospital-based	10380	27	26	42	High
Zash et al. [63]	2019	Botswana	Southern Africa	Cross-sectional	Hospital-based	119477	98	8.2	55	Medium