TABLE 1.
Summary of the clinical details of the human postmortem cases
| Age | Sex | PMI | A | C | B | Braak | Clinical assessment | COD | Race |
|---|---|---|---|---|---|---|---|---|---|
| Low AD | |||||||||
| 188 | F | 9.00 | 1 | 1 | 1 | Stage I | No Cognitive Disorder | Arteriovascular sclerotic disease | Caucasian |
| 287 | M | 8.00 | 1 | 0 | 1 | Stage I | No Cognitive Disorder | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 386 | F | 37.00 | 1 | 0 | 1 | Stage II | No Cognitive Disorder | urethral cancer, heart murmur | Caucasian |
| 489 | F | 4.55 | 1 | 1 | 1 | Stages I–II | No Cognitive Disorder | Coronary Artery Disease; Atrial fibrillation; Hypertension | Caucasian |
| 596 | F | 6.00 | 0 | 1 | 1 | Stages I–II | No Cognitive Disorder | Generalized atherosclerosis | Caucasian |
| 691 | F | 18.66 | 0 | 0 | 1 | Stage I | No Cognitive Disorder | End Stage Congestive Heart Failure | Caucasian |
| 792 | F | 22.30 | 1 | 0 | 1 | Stage II | No Cognitive Disorder | Atherosclerotic Heart Disease | Caucasian |
| 872 | M | 17.25 | 0 | 0 | 1 | Stage I | No Cognitive Disorder | Atherosclerotic Coronary Artery Disease, Ischemic Cardiomyopathy | Caucasian |
| 972 | M | 17.66 | 0 | 0 | 0 | Stage 0 | No Cognitive Disorder | Acute Myocardial Infarction; Diabetes Mellitus | Caucasian |
| 1073 | M | 20.50 | 2 | 0 | 1 | Stage I | No Cognitive Disorder | Atherosclerotic Heart Disease; Cardiomyopathy; Diabetes | Caucasian |
| 1174 | F | 34.9 | 1 | 0 | 1 | Stage I | No Cognitive Disorder | chronic kidney disease | Caucasian |
| 1267 | F | 25.95 | 1 | 0 | 1 | Stage 1 | No Cognitive Disorder | Atherosclerotic Coronary Artery Disease, Tobacco Abuse, Hypertension | Caucasian |
| 1394 | M | 23.40 | 2 | 0 | 1 | Stage 1 | No Cognitive Disorder | Congestive Heart Failure | Caucasian |
| 1490 | F | 24.30 | 1 | 1 | 1 | Stage II | No Cognitive Disorder | Cardiac Arrest; Respiratory Arrest; Unspecified Natural | Caucasian |
| Causes; Cardiovascular Disease | |||||||||
| 1593 | M | 16.88 | 1 | 1 | 1 | Stages I–II | No Cognitive Disorder | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 1672 | M | 24.28 | 1 | 0 | 0 | Stage 0 | No Cognitive Disorder | Acute Myocardial Infarction caused by Hypertensive | Caucasian |
| Arteriosclerotic Cardiovascular Disease | |||||||||
| 17102 | F | 10.30 | 0 | 0 | 1 | Stage II | No Cognitive Disorder | Failure to thrive | Caucasian |
| Mean 84.588 | 18.88 | ||||||||
| Intermediate AD | |||||||||
| 192 | M | 12.00 | 3 | 3 | 2 | Stages III–IV | Moderate | Acute Renal Failure | Caucasian |
| 290 | F | 8.48 | 2 | 3 | 2 | Stage III | Moderate | Acute Renal Failure | Caucasian |
| 390 | F | 22.12 | 2 | 3 | 2 | Stages III–IV | Severe | Advanced Dementia; vascular | Caucasian |
| 491 | F | 15.00 | 3 | 2 | 2 | Stage III | Moderate | Lung cancer | Caucasian |
| 579 | F | 18.28 | 2 | 3 | 2 | Stage III | Moderate | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 682 | M | 17.60 | 2 | 3 | 2 | Stages III–IV | Moderate | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 794 | F | 18.45 | 2 | 2 | 2 | Stages III–IV | Moderate | Cardiopulmonary Arrest | Caucasian |
| 882 | M | 18.22 | 2 | 2 | 2 | Stages III–IV | Moderate | Cardiac Arrest; Vascular Dementia | Caucasian |
| 987 | M | 13.91 | 2 | 3 | 3 | Stages V–VI | Moderate | Sepsis caused by urinary tract infection | Caucasian |
| 1080 | M | 10.53 | 3 | 2 | 3 | Stages V–VI | Moderate | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 1178 | M | 14.51 | 2 | 2 | 2 | Stages III–IV | Moderate | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 1278 | F | 6.00 | 2 | 2 | 2 | Stages III–IV | Moderate | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 1379 | F | 6.40 | 1 | 3 | 3 | Stages V–VI | Severe | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 1466 | F | 44.25 | 3 | 3 | 2 | Stages III–IV | Moderate | Urinary Tract Infection | Caucasian |
| 1583 | M | 15.12 | 2 | 2 | 2 | Stages III–IV | Moderate | Liver Failure | Caucasian |
| 1677 | F | 10.75 | 2 | 2 | 2 | Stage III | Moderate | Cardiac Arrest; Atherosclerotic Disease | Caucasian |
| 1790 | F | 13.25 | 2 | 1 | 2 | Stages III–IV | Moderate | Lung Cancer | Caucasian |
| Mean 83.412 | 15.58 |
Note: PMI = postmortem interval; Yr = year; A Score = Aβ immunopositivity, Thal Phase; C Score = neuritic plaque density, CERAD; B Score = Neurofibrillary tangles; COD = Cause of Death; AD = Alzheimer's disease; M = male; F = female; No Cognitive Disorder ≥62% on Modified Telephone Interview for Cognitive Status (TICS‐M; score 61–54%); Moderate = Moderate dementia; Severe = Severe dementia.