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. 2023 Jun 7;618(7967):1085–1093. doi: 10.1038/s41586-023-06169-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — pH sensitivity of the GloSensor cAMP responses of PTH1R upon stimulation with PTH and PCO371. Note that we adjusted the assay buffer (See also Methods) to the indicated pH. Symbols and error bars represent mean and SEM, respectively, of three independent experiments with each performed in duplicate.