Fig. 5. Xenograft model. The combination of DZNep (2 mg/kg) and TRAIL (0.2 mg/mL) significantly decreases the tumor size compared to each treatment alone and the control (A). There are no differences in body weight between the four groups (B). After 4 weeks, the tumors are extracted and size and weight are evaluated (C, D). ns: not significant, TRAIL: tumor necrosis factor-related apoptosis-inducing ligand. ^**p<0.01, ^***p<0.001.