Table 8. Recommendations – follow-up.
| Follow-up on men on testosterone therapy | LoE | Grade |
|---|---|---|
| Assess the response to therapy at 3, 6 to 12 months, and every 12 months thereafter | 4 | C |
| Aim for a target level of total testosterone 15–30 nmol/L to achieve optimal response | 4 | C |
| Monitor haematocrit before treatment, at 3–6 months, 12 months and every 12 months thereafter. Decrease dosage, or switch preparation, if haematocrit >0.54. If haematocrit remains elevated, consider stopping and re-introduce at a lower dose | 4 | C |
| Assess prostate health by PSA and, ideally, DRE before commencing TRT followed by PSA at 3–6 months, 12 months and every 12 months thereafter | 4 | C |
| Assess cardiovascular risk before TRT is initiated and monitor cardiovascular risk factors throughout therapy | 1b | A |
PSA: prostate specific antigen, DRE: digital rectal examination, TRT: testosterone replacement therapy.