Table 3. Logistic regression analyses investigating association between cannabis use and semen parameters.
| Semen parameter | unOR (95% CI) | p-value | aOR (95% CI)a | p-value | ||
|---|---|---|---|---|---|---|
| Concentration <15 (106/mL) | ||||||
| Cannabis use (lifetime) | ||||||
| No | Reference | - | Reference | - | ||
| Yes | 1.42 (0.31–7.61) | 0.708 | 1.08 (0.03–41.25) | 0.920 | ||
| Days of cannabis use (use in last 30 d) | 0.78 (0.07–4.13) | 0.827 | 1.07 (0.30–3.79) | 0.923 | ||
| Days of cannabis use (use in last 12 mo) | 1.50 (0.90–2.33) | 0.139 | 1.79 (0.55–12.47) | 0.945 | ||
| Total count <39 (106 per ejaculate) | ||||||
| Cannabis use (lifetime) | ||||||
| No | Reference | - | Reference | - | ||
| Yes | 2.45 (0.65–12.19) | 0.296 | 1.57 (0.28–8.95) | 0.640 | ||
| Days of cannabis use (use in last 30 d) | 2.53 (0.63–9.43) | 0.245 | 1.24 (0.30–5.67) | 0.250 | ||
| Days of cannabis use (use in last 12 mo) | 1.82 (0.23–2.70) | 0.110 | 0.79 (0.07–8.98) | 0.846 | ||
| Morphology <4 (% of normal forms) | ||||||
| Cannabis use (lifetime) | ||||||
| No | Reference | - | Reference | - | ||
| Yes | 1.18 (0.37–3.90) | 0.814 | 1.36 (0.22–16.55) | 0.653 | ||
| Days of cannabis use (use in last 30 d) | 1.65 (0.44–5.39) | 0.503 | 1.85 (0.42–7.34) | 0.470 | ||
| Days of cannabis use (use in last 12 mo) | 1.06 (0.60–1.59) | 0.847 | 1.06 (0.60–1.69) | 0.835 | ||
| Total motility <40 (% of motile sperm cells) | ||||||
| Cannabis use (lifetime) | ||||||
| No | Reference | - | Reference | - | ||
| Yes | 1.03 (0.50–2.13) | 0.942 | 1.55 (0.89–22.31) | 0.761 | ||
| Days of cannabis use (use in last 30 d) | 1.91 (0.88–4.18) | 0.171 | 2.31 (0.93–5.84) | 0.131 | ||
| Days of cannabis use (use in last 12 mo) | 1.21 (0.90–1.65) | 0.927 | 1.37 (0.96–2.01) | 0.156 | ||
unOR: unadjusted odds ratio, CI: confidence interval, aOR: adjusted odds ratio, -: not available.
aAdjusted for age, body mass index, smoke, hard drugs, alcohol, general health, and education.