Table 7.
Effect of methanolic extract of Myrica nagi (MEMN) on liver enzymes in a high-fat diet (HFD), GTG model.
| a | ||
|---|---|---|
| Group | SGPT U/L | ALP U/L |
| Control | 32.79 ± 0.71 | 224.25 ± 4.69 |
| HFD | 81.21 ± 1.8### | 422.12 ± 0.95### |
| Orlistat (10 mg/kg) | 73.06 ± 0.98∗ | 373.06 ± 2.92∗∗∗ |
| MEMN (100 mg/kg) | 70.04 ± 1.25∗ | 370.04 ± 2.35∗∗∗ |
| MEMN (200 mg/kg) | 64.25 ± 0.99∗∗ | 364.25 ± 1.68∗∗∗ |
| MEMN (400 mg/kg) | 43.18 ± 0.82∗∗∗ | 343.18 ± 2.29∗∗∗ |
| b | ||
|---|---|---|
| Groups/Treatment | ALP (U/L) | SGPT (U/L) |
| Normal Control | 37.33 ± 1.202 | 31.33 ± 1.202 |
| Gold thioglucose (300 mg/kg, i.p.) | 68.66 ± 2.028## | 65.66 ± 1.764## |
| GTG + Orlistat (10 mg/kg, p.o.) | 42.66 ± 2.333∗∗ | 41.66 ± 0.881∗∗ |
| GTG + MEMN (100 mg/kg, p.o.) | 58.33 ± 1.453∗∗ | 56 ± 0.577∗∗ |
| GTG + MEMN (200 mg/kg, p.o.) | 46.66 ± 1.202∗∗ | 46 ± 1.732∗∗ |
| GTG + MEMN (400 mg/kg, p.o.) | 45.69 ± 1.202∗∗ | 44.20 ± 1.512∗∗ |
SGPT, serum glutamate-pyruvate transaminase; ALP, Alkaline phosphatase. Methanolic extract of M. nagi., MEMN; GTG., Gold thio glucose; p.o., per oral. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ###p < 0.001, #p < 0.05, ##p < 0.01, #When compared with normal control group, ∗when compared with inducer group.