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. 2023 Jun 28;71(1):16. doi: 10.1007/s00005-023-00682-z

Table 1.

Kidney status of glutathione metabolism in the experimental groups

Parameters NaCl LA LPS LPS + LA
Total GSH (µM) 82.8 ± 13.7 77.6 ± 47.9 12.5 ± 5.6** 93.8 ± 39.1*
GSH (µM) 69.5 ± 16.7 56.2 ± 13.8 4.9 ± 5.6** 89.9 ± 14.7*
GSSG (µM) 19.8 ± 8.2 5.7 ± 2.7& 18.9 ± 5.8## 19.1 ± 3.4
GSH/GSSG (redox status) 3.0 ± 2.1 5.9 ± 1.3 0.2 ± 0.3#,** 3.9 ± 1.2*

Values are expressed as mean ± SD, n = 8 in each group. One-way ANOVA showed significant differences in total GSH, GSH, GSSG and GSH/GSSG concentrations between different treatment groups (F = 527.54; F = 2009.38; F = 650.08; F = 1034.78, respectively; df = 3; P < 0.001)

*P < 0.05 vs. LPS;

**P < 0.01 vs. NaCl, LA;

#P < 0.05 vs. NaCl;

##P < 0.001 vs. LA;

&P < 0.01 vs. NaCl