Table 2.

Effect of α-LA, LPS and their combination on TNF-α and IL-6 levels in kidney homogenates

Parameters	NaCl	LA	LPS	LPS + LA
TNF-α (pg/mL)	34.7 ± 21.2	42.2 ± 28.1	188.3 ± 47.3*,#	96.4 ± 23.2**,&
IL-6 (pg/mL)	27.7 ± 9.1	33.5 ± 11.1	168.4 ± 40.8*,#	83.2 ± 20.1**,&

Values are expressed as mean ± SD, n = 8 in each group. One-way ANOVA showed significant differences in TNF-α and IL-6 concentrations between different treatment groups (F = 1437.14 and F = 1684.47, respectively; df = 3; P < 0.001)

*P < 0.001 vs. Control;

**P < 0.05 vs. LPS;

^#P < 0.01 vs. LA