Table 1.

Clinical information of the discovery cohort

ID	Group	WHO/ ISUP	Pathological Stage	SEX	AGE	SIDE	Pathological Diagnosis
1	LccRCC	I	I	MALE	51	Left	ccRCC
2	LccRCC	I	I	FEMALE	41	Right	ccRCC
3	LccRCC	I	I	MALE	43	Left	ccRCC
4	LccRCC	I	I	MALE	66	Left	ccRCC
5	LccRCC	I	I	MALE	46	Right	ccRCC
6	LccRCC	II	I	MALE	56	Right	ccRCC with degeneration and hemorrhage
7	LccRCC	II	I	FEMALE	46	Left	ccRCC
8	LccRCC	II	I	MALE	44	Right	ccRCC
9	LccRCC	II	I	MALE	36	Right	ccRCC
10	LccRCC	III	I	FEMALE	72	Tight	ccRCC
11	LccRCC	III	I	MALE	63	Right	ccRCC with hemorrhage
12	LccRCC	III	I	FEMALE	53	Right	ccRCC with necrosis
13	LccRCC	III	I	FEMALE	67	Left	ccRCC
14	LccRCC	III	I	MALE	69	Left	ccRCC
15	LccRCC	IV	I	MALE	59	Left	ccRCC with sacromatoid
16	AccRCC	II	IV	MALE	55	Right	recurrent ccRCC
17	AccRCC	I-II	IV	FEMALE	57	Right	ccRCC with lung metastasis
18	AccRCC	II	IV	MALE	69	Right	ccRCC with thrombus, adrenal invasion and paravena cava lymph nodes metastasis
19	AccRCC	III	IV	MALE	39	Left	recurrent ccRCC with necrosis
20	AccRCC	III	IV	MALE	73	Left	recurrent ccRCC with necrosis
21	AccRCC	III	IV	MALE	67	Right	ccRCC with bone metastasis
22	AccRCC	IV	IV	MALE	68	Left	ccRCC with thrombus,renal sinus fat invasion,and para-aortic lymph nodes in hilum metastasis
23	AccRCC	III-IV	IV	MALE	68	Right	ccRCC with degeneration, necrosis, and lymphocytes infiltration