Table 2.

Asymmetric experimental matrix of CT-CTO-NEs stability in sodium alginate solution and cross-linked film.

Experimental	Name	X1	X2	PDI	DS
1	CT-CTO-NE1	− 1	− 1	PDI 1	DS 1
2	CT-CTO-NE2	0	− 1	PDI 2	DS 2
3	CT-CTO-NE3	1	− 1	PDI 3	DS 3
4	CT-CTO-NE4	2	− 1	PDI 4	DS 4
5	CT-CTO-NE5	3	− 1	PDI 5	DS 5
6	CT-CTO-NE6	4	− 1	PDI 6	DS 6
7	CT-CTO-NE7	5	− 1	PDI 7	DS 7
8	CT-CTO-NE8	6	− 1	PDI 8	DS 8
9	CT-CTO-NE9	− 1	+ 1	PDI 9	DS 9
10	CT-CTO-NE10	0	+ 1	PDI 10	DS 10
11	CT-CTO-NE11	1	+ 1	PDI 11	DS 11
12	CT-CTO-NE12	2	+ 1	PDI 12	DS 12
13	CT-CTO-NE13	3	+ 1	PDI 13	DS 13
14	CT-CTO-NE14	4	+ 1	PDI 14	DS 14
15	CT-CTO-NE15	5	+ 1	PDI 15	DS 15
16	CT-CTO-NE16	6	+ 1	PDI 16	DS 16

Experimental: Different freshly prepared CT-CTO-NEs in sodium alginate solution and cross-linked film.

PDI Polydispersity index of freshly prepared CT-CTO-NEs in sodium alginate solution and cross-linked film, DS droplet size of freshly prepared CT-CTO-NEs in sodium alginate solution and cross-linked film. CT-CTO-NE1-8 Final concentration of CT-CTO at 0.05% w/w, CT-CTO-NE9-16 Final concentration of CT-CTO at 0.1% w/w.