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. 2023 Jun 28;13:10485. doi: 10.1038/s41598-023-34060-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Protective effect of amifostine (AMI) on bleomycin (BLM)-induced pulmonary fibrosis in mice. (a) Hematoxylin and eosin staining of lung tissue sections (magnification × 100 and × 200). (b) Masson staining of lung tissue sections (magnification × 100 and × 200). (c) Ashcroft score was used to determine the degree of pulmonary fibrosis. (d) Content of hydroxyproline in lung tissue. Data are expressed as mean ± SD (n = 6). ^⁎⁎⁎P < 0.001 versus the control group. ^###P < 0.001 and ^#P < 0.05 versus the model group. ^&&&P < 0.001 and ^&P < 0.05 versus the AMI 200-mg/kg group.