Table 1.
Nonalcoholic fatty liver disease activity scores.
| Liver samples | Histologic feature | Fibrosis grade | |
|---|---|---|---|
| Human | Healthy liver | 0 | 0 |
| NAFLD liver | 6 ± 1 | 3 ± 1 | |
| Mouse | ND AD-anti-miR-NC | 0 | 0 |
| ND AD-anti-miR-28a-5p | 0 | 0 | |
| HFD AD-anti-miR-NC | 5 ± 1 | 2 ± 1 | |
| HFD AD-anti-miR-28a-5p | 2 ± 1 | 1 ± 1 | |
| C57 BL/6 AD-vector + AD-miR-NC | 0 | 0 | |
| Ob/Ob AD-vector + AD-miR-NC | 6 ± 1 | 2 ± 1 | |
| Ob/Ob AD-GAS5 + AD-miR-NC | 2 ± 1 | 1 ± 1 | |
| Ob/Ob AD-GAS5 + AD-miR-28a-5p | 5 ± 1 | 2 ± 1 | |
| C57 BL/6 AD-anti-miR-NC + AD-sh-NC | 0 | 0 | |
| Ob/Ob AD-anti-miR-NC + AD-sh-NC | 6 ± 1 | 2 ± 1 | |
| Ob/Ob AD-sh-miR-28a-5p + AD-miR-NC | 2 ± 1 | 1 ± 1 | |
| Ob/Ob AD-sh-miR-28a-5p + AD-sh-MARCH7 | 4 ± 1 | 2 ± 1 | |
| C57 BL/6 AD-vector | 0 | 0 | |
| Ob/Ob AD-vector | 6 ± 1 | 2 ± 1 | |
| Ob/Ob AD-MARCH7-WT | 2 ± 1 | 1 ± 1 | |
| Ob/Ob AD-MARCH7-Mut | 5 ± 1 | 2 ± 1 |