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. 2023 Apr 29;129(1):122–134. doi: 10.1038/s41416-023-02287-x

Table 2.

Post hoc tests for clinical and pathological characteristics which were found to significantly differ between the HER2-negative, HER2-low, and HER2-positive primary breast tumours using the Bonferroni method.

HER2-negative vs. HER2-low tumours HER2-negative vs. HER2-positive tumours HER2-low vs. HER2-positive tumours
Unifocal tumour
 P values 0.107 <0.001 <0.001
Histology
 P values 0.189 0.009 <0.001
Tumour Size
 P values 0.013 0.055 0.919
E&E grade
 P values 0.581 0.002 0.003
Nuclear grade
 P values 0.015 0.001 <0.001
Lymph node status
 P values 0.024 0.033 0.169
Disease stage
 P values 0.162 <0.001 0.016
Oestrogen receptor expression
 P values 0.015 <0.001 <0.001
Progesterone receptor expression
 P values 0.025 <0.001 <0.001
Time to recurrence
 P values 0.643 0.007 0.039

E&E Elston and Ellis, HER2 human epidermal growth factor receptor 2.

Values in bold italic show statistically significant P-values.