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. 2023 Jun 15;14:1186404. doi: 10.3389/fphar.2023.1186404

FIGURE 2.

FIGURE 2

COVID-19 CFR for female and male patients, and for younger vs older patients. (A) CFR in percent from FAERS COVID-19 data (all reports with COVID-19 as reaction and where patient sex is specified) for the US, in 20% vaccination coverage bins, with male patients shown in blue and female patients shown in green. (B) CFR in percent from FAERS COVID-19 data (all reports with COVID-19 as reaction and where patient age is specified) for the United States, in 20% vaccination coverage bins, with patients ≥65 years shown in blue and patients <65 years old shown in green. Bins are indicated as (lower bound, upper bound], and the baseline period is defined as the period before the first vaccination was administered. Since a coverage of 80% had not yet been achieved at the time of data collection, we denote bins starting from 60% or higher coverage as “> x,” indicating that these bins include all data from coverage levels higher than x. The 95% confidence intervals are estimated using bootstrap resampling, and asterisks mark data points where the CFR is significantly different from the CFR during the baseline period (p-value from resampling, Benjamini-Hochberg with an accepted FDR of 5% over all bins, sexes, and age groups). Abbreviations: CFR: Case Fatality Rate; FAERS: FDA Adverse Event Reporting System.