Table 1.
Training datasets used for HSF.
| Dataset | Contrasts | Subfields | Field | Age | Condition |
|---|---|---|---|---|---|
| Winterburn et al. (2013) | T1 and T2 | DG/CA/Sub | 3T | 29–57 | - |
| Kulaga-Yoskovitz et al. (2015) | T1 and T2 | DG/CA/Sub | 3T | 21–53 | - |
| Yushkevich et al. (2015b) | T1 and T2 | DG/CA1/CA2-3/Sub | 3T | MCI | |
| Hindy et al. (2016) | T2 | DG/CA1/CA2/CA3/Sub | 3T | 18–30 | - |
| Bouyeure et al. (2021) | T1 and T2 | DG/CA1/CA2-3/Sub | 3T | 4–12 | - |
| Yushkevich et al. (2010) | T1 and T2 | DG/CA1/CA2/CA3/Sub | 4T | 38–82 | MCI/AD |
| HIPlay7* | T1 and T2 | DG/CA1/CA2/CA3/Sub | 7T | 12–21 | TLE |
| Wisse et al. (2016) | T2 | DG/CA1/CA2/CA3/Sub | 7T | 50–68 | - |
| Berron et al. (2017) | T1 and T2 | DG/CA1/CA2/CA3/Sub | 7T | 19–32 | - |
| Haeger et al. (2020)** | T2 | DG/CA1/CA2/CA3/Sub | 7T | 50–70 | - |
| Shaw et al. (2020)** | T1 and T2 | DG/CA1/CA2/CA3/Sub | 7T | 23–29 | - |
| Lagarde et al. (2021)** | T2 | DG/CA1/CA2/CA3/Sub | 7T | 50–84 | SC/MCI/AD |
Description of the training database, alongside their manually segmented hippocampal subfields, namely the dentate gyrus (DG), the cornu ammonis (CA)1, CA2, and CA3. Included participants are either healthy, exhibiting mild cognitive impairments (MCI), Alzheimer's disease (AD), hippocampal sclerosis (SC), or temporal lobe epilepsy (TLE).
*
In-house dataset, ANR-16-NEUC-0001-01; Manual Segmentation on 23 controls and 4 temporal lobe epilepsies; 1 mm T1w and 0.125*0.125*1.2 mm T2w MRIs.
**
Manual segmentations on 7 subjects per dataset performed by the authors (CP, SP, MF, MB, and MN), following Berron et al. (2017).