Table 2.
Total 90 patients | ||
Necrotizing enterocolitis disease features | ||
Age at NEC onset (days; mean ± SEM) | 25.2±2.4 | |
Gestational age at birth (weeks; mean ± SEM) | 27.9±0.7 | |
Corrected gestational age at NEC onset (weeks; mean ± SEM) | 31.4±0.7 | |
Clinical presentation | ||
Abdominal distension | 83 (92%) | |
Bloody stools | 6 (6.7%) | |
Feeding intolerance | 4 (4.5%) | |
Radiological findings | ||
Pneumatosis, n (%) | 30 (33.3%) | |
Pneumoperitoneum, n (%) | 40 (45%) | |
Portal venous gas, n (%) | 4 (4.4%) | |
Surgery | ||
Length of bowel resected (cm; mean ± SEM) | 29.2±3.2 | |
Bowel resection region | ||
Small bowel, n (%) | 65 (72%) | |
Large bowel, n (%) | 1 (1%) | |
Small bowel + Large bowel, n (%) | 24 (27%) | |
Intestinal ostomy, n (%) | 73 (81.1%) | |
Post-operative systemic course | ||
Duration of antibiotics (days; mean ± SEM) | 11.2±0.08 | |
Assisted ventilation | ||
Room air, n (%) | 16 (17.8%) | |
Assisted ventilation (continuous positive air pressure/intubated), n (%) | 74 (82%) | |
Positive blood culture for sepsis, n (%) | 9 (10%) | |
Post-operative intestinal features | ||
Post-operative ileus [days; n (%)] | 16.49±0.13 | |
Post-operative day at starting enteral feedings (days; mean ± SEM) | 16.91±0.13 | |
Abdominal wound infection, n (%) | 15/76 (19.7%) | |
Intestinal adhesions, n (%) | 12/76 (15.8%) | |
Intestinal strictures, n (%) | 8/76 (10.5%) | |
Intestinal fistulas, n (%) | 3/76 (3.9%) | |
Feedings at start | ||
Mother’s own/donor milk, n (%) | 35 (38.4%) | |
Infant formula, n (%) | 55 (61.5%) | |
Day of attainment of full enteral feedings (120 mL/kg; mean ± SEM) | 75±0.48 | |
Duration of parenteral nutrition (days; mean ± SEM) | 86.48±0.55 | |
Short Bowel Syndrome, n (%) | 7 (10%) | |
Discharge | ||
Length of stay (days; mean ± SEM) | 132.7±9.1 | |
Death, n (%) | 38 (42.2%) |
Well-recorded data on feedings available for the years 2012–2015, since institution of electronic records.
Reliable, well recorded data on post-operative complications available on 76 of our 90 patients