Table 3.
All infants (n=90) | Survivors (n=52) | Died (n=38) | p-value |
---|---|---|---|
Prenatal information | |||
Pregnancy-induced hypertension, n (%) | 15 (28.84%) | 10 (26.3%) | 0.07 |
Chorioamnionitis, n (%) | 2 (3.84%) | 3 (7.89%) | 0.42 |
Antenatal steroids, n (%) | 28 (53.84%) | 16 (42.1%) | 0.45 |
Maternal Indomethacin, n (%) | 1 (1.92%) | 1 (2.63%) | 0.82 |
Infant Demographics | |||
Birth weight (grams; mean ± SEM) | 1109.58±5.58 | 837.85±8.98 | <0.001 |
Gestational age (weeks; mean ± SEM) | 29.07±0.09 | 26.12±0.5 | <0.001 |
Small for gestational age, n (%) | 8 (15.38%) | 6 (15.78%) | 0.34 |
Male gender, n (%) | 34 (65.38%) | 22 (57.89%) | 0.33 |
African American ethnicity | 47 (90.4%) | 33 (86.84%) | 0.23 |
Cesarean section delivery | 28 (53.84%) | 20 (52.63%) | 0.88 |
Outborn | 30 (57.69%) | 15 (39.47%) | 0.77 |
Infant medical information prior to necrotizing enterocolitis | |||
5 minute Apgar score 0–5, n (%) | 7 (13.46%) | 9 (23.7%) | 0.62 |
Start enteral feedings (days, mean ± SEM) | 2.3±0.62 | 2.1±0.28 | 0.73 |
Enteral feedings | |||
Mother’s own/donor milk, n (%) | 20 (38.46%) | 18 (47.36%) | 0.39 |
Infant formula, n (%) | 32 (61.53%) | 20 (52.63%) | 0.39 |
Patent Ductus Arteriosus, n (%) | 40 (53.33%) | 22 (57.9%) | 0.005 |
Patent ductus arteriosus, medically treated, n (%) | 12 (30%) | 10 (45.45%) | 0.32 |
Patent ductus arteriosus, surgically ligated, n (%) | 2 (3.84%) | 0 (0%) | 0.22 |
Necrotizing enterocolitis | |||
NEC age onset (days; mean ± SEM) | 23.16±0.21 | 29.68±0.72 | 0.46 |
Length bowel resected (centimeters; mean ± SEM) | 23.10±0.25 | 36.28±0.95 | 0.034 |
Pressor support 24 hours after NEC onset, n (%) | 32 (61.53%) | 23 (60.5%) | 0.63 |
Post-operative Ileus (days; mean ± SEM) | 17.1±0.14 | 19.9±0.66 | 0.55 |
Days of parenteral nutrition (days; mean ± SEM) | 90.52±0.53 | 78.5±1.4 | 0.47 |
Day of starting feeds (days; mean ± SEM) | 17.31±0.14 | 16.27±0.3 | 0.97 |
Day to reach full feeds (days; mean ± SEM) | 81.86±0.49 | 52.62±0.87 | 0.06 |
Antibiotic days (days; mean ± SEM) | 11.67±0.09 | 10.14±0.17 | 0.47 |
Length of hospital stay (days; mean ± SEM) | 157.53±0.87 | 97.51±2.14 | 0.014 |
SEM = standard error of mean