Skip to main content
. Author manuscript; available in PMC: 2023 Jun 29.
Published in final edited form as: J Perinatol. 2020 Jul 15;40(11):1671–1678. doi: 10.1038/s41372-020-0728-8

Table 3.

Comparison of prenatal, neonatal, and NEC data in survivors and those who died.

All infants (n=90) Survivors (n=52) Died (n=38) p-value
Prenatal information
Pregnancy-induced hypertension, n (%) 15 (28.84%) 10 (26.3%) 0.07
Chorioamnionitis, n (%) 2 (3.84%) 3 (7.89%) 0.42
Antenatal steroids, n (%) 28 (53.84%) 16 (42.1%) 0.45
Maternal Indomethacin, n (%) 1 (1.92%) 1 (2.63%) 0.82
Infant Demographics
Birth weight (grams; mean ± SEM) 1109.58±5.58 837.85±8.98 <0.001
Gestational age (weeks; mean ± SEM) 29.07±0.09 26.12±0.5 <0.001
Small for gestational age, n (%) 8 (15.38%) 6 (15.78%) 0.34
Male gender, n (%) 34 (65.38%) 22 (57.89%) 0.33
African American ethnicity 47 (90.4%) 33 (86.84%) 0.23
Cesarean section delivery 28 (53.84%) 20 (52.63%) 0.88
Outborn 30 (57.69%) 15 (39.47%) 0.77
Infant medical information prior to necrotizing enterocolitis
5 minute Apgar score 0–5, n (%) 7 (13.46%) 9 (23.7%) 0.62
Start enteral feedings (days, mean ± SEM) 2.3±0.62 2.1±0.28 0.73
Enteral feedings      
 Mother’s own/donor milk, n (%) 20 (38.46%) 18 (47.36%) 0.39
 Infant formula, n (%) 32 (61.53%) 20 (52.63%) 0.39
Patent Ductus Arteriosus, n (%) 40 (53.33%) 22 (57.9%) 0.005
Patent ductus arteriosus, medically treated, n (%) 12 (30%) 10 (45.45%) 0.32
Patent ductus arteriosus, surgically ligated, n (%) 2 (3.84%) 0 (0%) 0.22
Necrotizing enterocolitis
NEC age onset (days; mean ± SEM) 23.16±0.21 29.68±0.72 0.46
Length bowel resected (centimeters; mean ± SEM) 23.10±0.25 36.28±0.95 0.034
Pressor support 24 hours after NEC onset, n (%) 32 (61.53%) 23 (60.5%) 0.63
Post-operative Ileus (days; mean ± SEM) 17.1±0.14 19.9±0.66 0.55
Days of parenteral nutrition (days; mean ± SEM) 90.52±0.53 78.5±1.4 0.47
Day of starting feeds (days; mean ± SEM) 17.31±0.14 16.27±0.3 0.97
Day to reach full feeds (days; mean ± SEM) 81.86±0.49 52.62±0.87 0.06
Antibiotic days (days; mean ± SEM) 11.67±0.09 10.14±0.17 0.47
Length of hospital stay (days; mean ± SEM) 157.53±0.87 97.51±2.14 0.014

SEM = standard error of mean